Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptide
Quick Overview for Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptide (ABIN8096961)
Target
Source
Application
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Purpose
- CHRNA7 Peptide
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Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) peptide
CHRNA7 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CHRNA7 antibody ( ARP35418_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
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Background
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Targeted Subunit: alpha-7
Background Information: The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
Alternative Symbols: NACHRA7, CHRNA7-2
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Molecular Weight
- 56kDa
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Gene ID
- 1139
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NCBI Accession
- NP_000737
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UniProt
- P36544
Target
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