Chymotrypsin-Like Elastase Family, Member 1 (CELA1) (N-Term) Peptide
Quick Overview for Chymotrypsin-Like Elastase Family, Member 1 (CELA1) (N-Term) Peptide (ABIN8097457)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- ELA1 Peptide - N-terminal region
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Chymotrypsin-Like Elastase Family, Member 1 (CELA1) peptide (Ovalbumin)
CELA1 Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ELA1 antibody ( ARP52007_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CELA1 (Chymotrypsin-Like Elastase Family, Member 1 (CELA1))
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Background
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Background Information: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 (ELA1) expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-867 BC069454.1 1-867 868-952 AF120493.1 868-952
Alternative Symbols: ELA1
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Molecular Weight
- 28kDa
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Gene ID
- 1990
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NCBI Accession
- NP_001962
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UniProt
- Q9UNI1
Target
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