Cysteine-Rich Secretory Protein 1 (CRISP1) (N-Term) Peptide
Quick Overview for Cysteine-Rich Secretory Protein 1 (CRISP1) (N-Term) Peptide (ABIN8098261)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- CRISP1 Peptide - N-terminal region
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Sequence
- ARIFSKYCDM TESNPLERRL PNTFCGENMH MTSYPVSWSS VIGVWYSEST
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CRISP1 Antibody (ARP53581_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
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Background
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Background Information: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.
Alternative Symbols: AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
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Molecular Weight
- 27kDa
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Gene ID
- 167
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NCBI Accession
- NP_001122
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UniProt
- P54107
Target
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