Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide
Quick Overview for Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide (ABIN8098708)
Target
Source
Application
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Purpose
- DEAF1 Peptide
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-DEAF1 antibody ( ARP39467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
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Background
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Background Information: DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alternative Symbols: NUDR, SPN, ZMYND5
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Molecular Weight
- 59kDa
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Gene ID
- 10522
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NCBI Accession
- NP_066288
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UniProt
- O75398
Target
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