Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide
Quick Overview for Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide (ABIN8098743)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- DAZL Peptide - middle region
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Sequence
- EATPPSGNGP QKKSVDRSIQ TVVSCLFNPE NRLRNSVVTQ DDYFKDKRVH
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Deleted in Azoospermia-Like (DAZL) peptide
DAZL Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- DAZL Antibody (ARP88099_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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Background
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Background Information: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: DAZH, DAZL1, DAZLA, SPGYLA
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Molecular Weight
- 32 kDa
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Gene ID
- 1618
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NCBI Accession
- NP_001177740
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UniProt
- Q92904
Target
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