Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide
DKK2
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN8098865
$145.08
Plus shipping costs $50.00
100 μg
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Quick Overview for Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide (ABIN8098865)
Target
DKK2
(Dickkopf 2 Homolog (DKK2))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Purpose
- Dkk2 Peptide - middle region
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Sequence
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
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Dickkopf 2 Homolog (DKK2) peptide
DKK2 Reactivity: Mouse, Human, Cow, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody (ARP55047_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Background
- Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
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Molecular Weight
- 28kDa
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Gene ID
- 56811
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NCBI Accession
- NP_064661
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UniProt
- Q9QYZ8
Target
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