Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptide
Quick Overview for Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptide (ABIN8099464)
Target
Source
Application
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Protein Region
- Middle Region
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Purpose
- ENPP6 Peptide - middle region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ENPP6 antibody ( ARP53158_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))
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Background
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Background Information: ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
Alternative Symbols: MGC33971, NPP6
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Molecular Weight
- 50kDa
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Gene ID
- 133121
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NCBI Accession
- NP_699174
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UniProt
- Q6UWR7
Target
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