EPH Receptor B2 (EPHB2) (C-Term) Peptide
Quick Overview for EPH Receptor B2 (EPHB2) (C-Term) Peptide (ABIN8099714)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- EPHB2 Peptide - C-terminal region
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Sequence
- PRATGRTKRC QPRDVTKKTC NSNDGKKKGM GKKKTDPGRG REIQGIFFKE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-EPHB2 Antibody (ARP78020_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- EPH Receptor B2 (EPHB2)
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Background
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Background Information: This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Alternative Symbols: DRT, EK5, ERK, CAPB, Hek5, PCBC, EPHT3, Tyro5
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Molecular Weight
- 116 kDa
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Gene ID
- 2048
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NCBI Accession
- NP_004433
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UniProt
- P29323
Target
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