Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptide
Quick Overview for Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptide (ABIN8099900)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- EEF1E1 Peptide - N-terminal region
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Sequence
- ELSLLEKSLG LSKGNKYSAQ GERQIPVLQT NNGPSLTGLT TIAAHLVKQA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- EEF1E1 Antibody (ARP85516_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
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Background
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Background Information: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alternative Symbols: P18, AIMP3
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Molecular Weight
- 20 kDa
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Gene ID
- 9521
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NCBI Accession
- NP_001129122
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UniProt
- O43324
Target
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