Eukaryotic Translation Initiation Factor 5A (EIF5A) (Middle Region) Peptide
Quick Overview for Eukaryotic Translation Initiation Factor 5A (EIF5A) (Middle Region) Peptide (ABIN8100006)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- EIF5A Peptide - middle region
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Sequence
- PNIKRNDFQL IGIQDGYLSL LQDSGEVRED LRLPEGDLGK EIEQKYDCGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- EIF5A Antibody (ARP88522_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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Background
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Background Information: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Alternative Symbols: EIF-5A, EIF5A1, eIF5AI
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Molecular Weight
- 20 kDa
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Gene ID
- 1984
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NCBI Accession
- NP_001137232
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UniProt
- P63241
Target
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