Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide
Quick Overview for Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide (ABIN8100668)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- FRS2 Peptide - middle region
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Sequence
- ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- FRS2 Antibody (ARP86887_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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Background
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Background Information: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Alternative Symbols: SNT, SNT1, FRS1A, FRS2A, SNT-1, FRS2alpha
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Molecular Weight
- 55 kDa
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Gene ID
- 10818
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NCBI Accession
- NP_001036020
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UniProt
- Q8WU20
Target
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