FK506 Binding Protein 4, 59kDa (FKBP4) (N-Term) Peptide
Quick Overview for FK506 Binding Protein 4, 59kDa (FKBP4) (N-Term) Peptide (ABIN8100739)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- FKBP4 Peptide - N-terminal region
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Sequence
- EGTGTETPMI GDRVFVHYTG WLLDGTKFDS SLDRKDKFSF DLGKGEVIKA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- FKBP4 Antibody (ARP90634_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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Background
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Background Information: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Alternative Symbols: p59, 59 kDa, FKBP-4, FKBP52, FKPB52, FKBP-52, AL022792, AW208983
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Molecular Weight
- 52 kDa
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Gene ID
- 14228
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NCBI Accession
- NP_034349
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UniProt
- P30416
Target
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