Folate Receptor 1 (Adult) (FOLR1) (Middle Region) Peptide
Quick Overview for Folate Receptor 1 (Adult) (FOLR1) (Middle Region) Peptide (ABIN8100805)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- FOLR1 Peptide - middle region
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Sequence
- LYRFNWNHCG TMTSECKRHF IQDTCLYECS PNLGPWIQQV DQSWRKERIL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- FOLR1 Antibody (ARP90429_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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Background
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Background Information: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.
Alternative Symbols: FBP1, Folbp1, Folbp-1
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Molecular Weight
- 28 kDa
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Gene ID
- 14275
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NCBI Accession
- NP_001239481
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UniProt
- P35846
Target
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