Frizzled-Related Protein (FRZB) (C-Term) Peptide
Quick Overview for Frizzled-Related Protein (FRZB) (C-Term) Peptide (ABIN8101003)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- FRZB Peptide - C-terminal region
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Sequence
- LCPPLTVNEE YVIMGYEDEE RSRLLLVEGS IAEKWKDRLG KKVKRWDMKL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- FRZB Antibody (ARP89621_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- FRZB (Frizzled-Related Protein (FRZB))
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Background
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Background Information: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity).
Alternative Symbols: Frp, Sfrp3, fritz, frzb-1, frezzled
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Molecular Weight
- 36 kDa
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Gene ID
- 20378
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NCBI Accession
- NP_035486
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UniProt
- P97401
Target
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