gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Peptide
Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Peptide (ABIN8101260)
Target
Source
Application
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Purpose
- GABRA1 Peptide
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gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) peptide
GABRA1 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GABRA1 antibody ( ARP34977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Background
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Targeted Subunit: alpha-1
Background Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Alternative Symbols: ECA4, EJM, EJM5
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Molecular Weight
- 52kDa
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Gene ID
- 2554
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NCBI Accession
- NP_000797
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UniProt
- P14867
Target
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