gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide
Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide (ABIN8101280)
Target
Source
Application
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Purpose
- GABRG2 Peptide
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gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) peptide
GABRG2 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GABRG2 antibody ( ARP35574_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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Background
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Targeted Subunit: gamma-2
Background Information: Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Alternative Symbols: CAE2, ECA2, GEFSP3
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Molecular Weight
- 36kDa
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Gene ID
- 2566
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NCBI Accession
- NP_944493
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UniProt
- P18507
Target
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