Glucokinase (Hexokinase 4) Regulator (GCKR) (N-Term) Peptide
Quick Overview for Glucokinase (Hexokinase 4) Regulator (GCKR) (N-Term) Peptide (ABIN8101535)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- GCKR Peptide - N-terminal region
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Sequence
- VIETPEPGKW ELSGYEAAVP ITEKSNPLTQ DLDKADAENI VRLLGQCDAE
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Glucokinase (Hexokinase 4) Regulator (GCKR) peptide
GCKR Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GCKR Antibody (ARP74540_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Background
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Background Information: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alternative Symbols: GCKR,
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Molecular Weight
- 68kDa
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Gene ID
- 2646
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NCBI Accession
- NP_001477
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UniProt
- Q14397
Target
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