Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3) (N-Term) Peptide
Quick Overview for Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3) (N-Term) Peptide (ABIN8101565)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- GBA3 Peptide - N-terminal region
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Sequence
- LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GBA3 Antibody(ARP57505_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
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Background
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Background Information: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).
Alternative Symbols: CBGL1, GLUC, KLrP, MGC104276, MGC126878
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Molecular Weight
- 54kDa
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Gene ID
- 57733
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NCBI Accession
- NP_066024
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UniProt
- Q9H227
Target
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