Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide
Quick Overview for Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide (ABIN8101591)
Target
Origin
Source
Application
-
-
Protein Region
- Middle Region
-
Purpose
- GRIA4 Peptide - middle region
-
Sequence
- RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL
-
-
Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) peptide
GRIA4 Reactivity: Human, Mouse, Rat, Cow Host: Synthetic BP, Imm
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-GRIA4 Antibody (ARP76224_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
-
Background
-
Background Information: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Alternative Symbols: GRIA4,GLUR4,
-
Molecular Weight
- 47kDa
-
Gene ID
- 2893
-
UniProt
- P48058
Target
-
