Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptide
Quick Overview for Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptide (ABIN8101660)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- GPX1 Peptide - middle region
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Sequence
- DPKLITWSPV CRNDVAWNFE KFLVGPDGVP LRRYSRRFQT IDIEPDIEAL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GPX1 Antibody (ARP77970_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Glutathione Peroxidase 1 (GPX1)
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Background
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Background Information: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Symbols: GPXD, GSHPX1
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Molecular Weight
- 22 kDa
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Gene ID
- 2876
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NCBI Accession
- NP_000572
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UniProt
- A0A087WUQ6
Target
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