GM2 Ganglioside Activator (GM2A) (N-Term) Peptide
Quick Overview for GM2 Ganglioside Activator (GM2A) (N-Term) Peptide (ABIN8101820)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- GM2A Peptide - N-terminal region
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Sequence
- SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GM2A Antibody(ARP46007_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GM2A (GM2 Ganglioside Activator (GM2A))
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Background
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Background Information: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alternative Symbols: SAP-3, GM2-AP
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Molecular Weight
- 18kDa
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Gene ID
- 2760
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NCBI Accession
- NP_000396
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UniProt
- P17900
Target
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