Growth Differentiation Factor 10 (GDF10) (C-Term) Peptide
Quick Overview for Growth Differentiation Factor 10 (GDF10) (C-Term) Peptide (ABIN8101939)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- GDF10 Peptide - C-terminal region
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Sequence
- LPGLDERPPR AHAQHFHKHQ LWPSPFRALK PRPGRKDRRK KGQEVFMAAS
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Growth Differentiation Factor 10 (GDF10) (AA 369-478) peptide
GDF10 Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-BMP3B Antibody (ARP76188_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GDF10 (Growth Differentiation Factor 10 (GDF10))
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Background
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Background Information: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.
Alternative Symbols: BIP, BMP3B, BMP-3b
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Molecular Weight
- 52kDa
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Gene ID
- 2662
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NCBI Accession
- NP_004953
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UniProt
- P55107
Target
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