Hepatocyte Nuclear Factor 4, alpha (HNF4A) (Middle Region) Peptide
Quick Overview for Hepatocyte Nuclear Factor 4, alpha (HNF4A) (Middle Region) Peptide (ABIN8102399)
Target
Source
Application
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Protein Region
- Middle Region
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Purpose
- HNF4A Peptide - middle region
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Hepatocyte Nuclear Factor 4, alpha (HNF4A) peptide
HNF4A Reactivity: Human, Pig, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-HNF4A antibody ( ARP45595_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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Background
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Background Information: The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.
Alternative Symbols: FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14, HNF4alpha
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Molecular Weight
- 49kDa
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Gene ID
- 3172
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NCBI Accession
- NP_001025174
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UniProt
- P41235
Target
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