Hexokinase 1 (HK1) (Middle Region) Peptide
Quick Overview for Hexokinase 1 (HK1) (Middle Region) Peptide (ABIN8102479)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- HK1 Peptide - middle region
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Sequence
- ILVKMAKEGL LFEGRITPEL LTRGKFNTSD VSAIEKNKEG LHNAKEILTR
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-HK1 Antibody (ARP61058_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Hexokinase 1 (HK1)
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Background
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Background Information: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alternative Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
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Molecular Weight
- 103kDa
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Gene ID
- 3098
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NCBI Accession
- NP_277033
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UniProt
- P19367
Target
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