Histone Deacetylase 6 (HDAC6) (C-Term) Peptide
Quick Overview for Histone Deacetylase 6 (HDAC6) (C-Term) Peptide (ABIN8102608)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- Hdac6 Peptide - C-terminal region
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Sequence
- VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Hdac6 Antibody (ARP38730_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Background
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Background Information: Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Alternative Symbols: Hd6, Hdac5, Sfc6, mHDA2
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Molecular Weight
- 126kDa
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Gene ID
- 15185
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NCBI Accession
- NP_034543
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UniProt
- Q9Z2V5
Target
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