HLA Class I alpha F (HLAF) (N-Term) Peptide
Quick Overview for HLA Class I alpha F (HLAF) (N-Term) Peptide (ABIN8102638)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- HLA-F Peptide - N-terminal region
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Sequence
- PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-HLA-F Antibody(ARP49410_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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Background
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Background Information: HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.
Alternative Symbols: CDA12, HLA-5.4, HLA-CDA12, HLAF
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Molecular Weight
- 48kDa
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Gene ID
- 3134
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NCBI Accession
- NP_001091949
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UniProt
- Q5JQI8
Target
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