Importin 8 (IPO8) (C-Term) Peptide
Quick Overview for Importin 8 (IPO8) (C-Term) Peptide (ABIN8103000)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- IPO8 Peptide - C-terminal region
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Sequence
- PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-IPO8 Antibody (ARP65771_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Importin 8 (IPO8)
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Background
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Background Information: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: FLJ26580, RANBP8
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Molecular Weight
- 96kDa
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Gene ID
- 10526
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NCBI Accession
- NP_001177924
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UniProt
- O15397
Target
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