Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptide
Quick Overview for Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptide (ABIN8103312)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- IL1RAP Peptide - C-terminal region
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Sequence
- LVQYKAVKET KVKELKRAKT VLTVIKWKGE KSKYPQGRFW KQLQVAMPVK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-IL1RAP Antibody (ARP79330_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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Background
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Background Information: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Alternative Symbols: IL1R3, C3orf13, IL-1RAcP
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Molecular Weight
- 62 kDa
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Gene ID
- 3556
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NCBI Accession
- NP_001161400
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UniProt
- Q9NPH3
Target
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