Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Middle Region) Peptide
Quick Overview for Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Middle Region) Peptide (ABIN8103412)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- IRAK3 Peptide - middle region
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Sequence
- EDDESQNNNL LPSDEGLRID RMTQKTPFEC SQSEVMFLSL DKKPESKRNE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- IRAK3 Antibody (ARP81054_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Background
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Background Information: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Alternative Symbols: ASRT5, IRAKM
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Molecular Weight
- 65 kDa
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Gene ID
- 11213
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NCBI Accession
- NP_001135995
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UniProt
- Q9Y616
Target
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