Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptide
Quick Overview for Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptide (ABIN8103413)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- IRAK4 Peptide - C-terminal region
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Sequence
- TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-IRAK4 Antibody (ARP61431_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Background
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Background Information: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: IPD1, NY-REN-64, REN64, IRAK-4
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Molecular Weight
- 36kDa
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Gene ID
- 51135
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NCBI Accession
- NP_001138728
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UniProt
- Q9NWZ3
Target
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