Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (Middle Region) Peptide
Quick Overview for Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (Middle Region) Peptide (ABIN8103511)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- IDH3A Peptide - middle region
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Sequence
- WEERNVTAIQ GPGGKWMIPP EAKESMDKNK MGLKGPLKTP IAAGHPSMNL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- IDH3A Antibody (ARP90970_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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Background
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Background Information: Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Alternative Symbols: AA407078, AI316514, 1110003P10Rik, 1500012E04Rik
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Molecular Weight
- 40 kDa
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Gene ID
- 67834
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NCBI Accession
- NP_083849
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UniProt
- Q9D6R2
Target
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