Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptide
Quick Overview for Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptide (ABIN8103608)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- KALRN Peptide - middle region
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Sequence
- QGDSADEKSK KGWGEDEPDE ESHTPLPPPM KIFDNDPTQD EMSSLLAARQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-KALRN Antibody (ARP78863_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- KALRN (Kalirin, RhoGEF Kinase (KALRN))
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Background
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Background Information: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Symbols: DUO, CHD5, DUET, TRAD, CHDS5, HAPIP, ARHGEF24
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Molecular Weight
- 81 kDa
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Gene ID
- 8997
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NCBI Accession
- NP_001019831
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UniProt
- O60229
Target
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