Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptide
Quick Overview for Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptide (ABIN8104015)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- KREMEN1 Peptide - N-terminal region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-KREMEN1 antibody ( ARP44880_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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Background
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Background Information: KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alternative Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
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Molecular Weight
- 50kDa
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Gene ID
- 83999
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NCBI Accession
- NP_001034659
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UniProt
- Q96MU8
Target
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