Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide
Quick Overview for Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide (ABIN8104338)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- LZTS1 Peptide - N-terminal region
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Sequence
- LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG KSEDFFYIKV SQKARGSHHP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-LZTS1 Antibody (ARP72909_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
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Background
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Background Information: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Alternative Symbols: LZTS1, FEZ1,
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Molecular Weight
- 65kDa
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Gene ID
- 11178
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NCBI Accession
- XP_005273451
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UniProt
- Q9Y250
Target
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