Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptide
Quick Overview for Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptide (ABIN8104387)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- LAIR1 Peptide - C-terminal region
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Sequence
- LLVLFCLHRQ NQIKQGPPRS KDEEQKPQQR PDLAVDVLER TADKATVNGL
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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 22-125), (Extracellular Domain) peptide
LAIR1 Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-LAIR1 Antibody (ARP66044_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Background
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Background Information: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
Alternative Symbols: CD305, LAIR-1
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Molecular Weight
- 27kDa
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Gene ID
- 3903
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NCBI Accession
- NP_068352
Target
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