Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptide
Quick Overview for Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptide (ABIN8104640)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- LTB Peptide - N-terminal region
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Sequence
- AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-LTB Antibody(ARP45280_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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Background
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Background Information: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Symbols: TNFC, TNFSF3, p33
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Molecular Weight
- 25kDa
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Gene ID
- 4050
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NCBI Accession
- NP_002332
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UniProt
- Q06643
Target
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