Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide
Quick Overview for Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide (ABIN8104680)
Target
Source
Application
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Protein Region
- Middle Region
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Purpose
- LYCAT Peptide - middle region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-LYCAT antibody ( ARP44426_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
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Background
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Background Information: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alternative Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
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Molecular Weight
- 44kDa
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Gene ID
- 253558
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NCBI Accession
- NP_001002257
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UniProt
- Q6UWP7
Target
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