Mannosidase, Endo-alpha (MANEA) Peptide
Quick Overview for Mannosidase, Endo-alpha (MANEA) Peptide (ABIN8104844)
Target
Source
Application
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Purpose
- MANEA Peptide
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-MANEA antibody ( ARP49845_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MANEA (Mannosidase, Endo-alpha (MANEA))
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Background
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Background Information: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
Alternative Symbols: DKFZp686D20120, FLJ12838, hEndo, ENDO
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Molecular Weight
- 54kDa
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Gene ID
- 79694
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NCBI Accession
- NP_078917
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UniProt
- Q5SRI9
Target
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