Mitochondrial Translational Release Factor 1-Like (MTRF1L) (N-Term) Peptide
Quick Overview for Mitochondrial Translational Release Factor 1-Like (MTRF1L) (N-Term) Peptide (ABIN8105595)
Target
Origin
Source
Application
-
-
Protein Region
- N-Term
-
Purpose
- MTRF1L Peptide - N-terminal region
-
Sequence
- MRSRVLWGAA RWLWPRRAVG PARRPLSSGS PPLEELFTRG GPLRTFLERQ
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-RF1ML Antibody (ARP56319_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- MTRF1L (Mitochondrial Translational Release Factor 1-Like (MTRF1L))
-
Background
-
Background Information: The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants.
Alternative Symbols: MRF1L, HMRF1L, mtRF1a
-
Molecular Weight
- 29 kDa
-
Gene ID
- 54516
-
NCBI Accession
- NP_001107656
-
UniProt
- Q9UGC7
Target
-
