Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptide
Quick Overview for Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptide (ABIN8105669)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- MAP3K14 Peptide - N-terminal region
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Sequence
- SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-MAP3K14 Antibody(ARP42161_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Background
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Background Information: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alternative Symbols: FTDCR1B, HS, HSNIK, NIK
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Molecular Weight
- 104kDa
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Gene ID
- 9020
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NCBI Accession
- NP_003945
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UniProt
- Q99558
Target
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