MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Middle Region) Peptide
Quick Overview for MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Middle Region) Peptide (ABIN8105790)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- MRE11 Peptide - middle region
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Sequence
- RFRETRQKNT NEEDDEVREA MTRARALRSQ SEESASAFSA DDLMSIDLAE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-MRE11A Antibody(ARP56645_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Background
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Background Information: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alternative Symbols: ATLD, HNGS1, MRE11A, MRE11B
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Molecular Weight
- 80kDa
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Gene ID
- 4361
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NCBI Accession
- NP_005582
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UniProt
- P49959
Target
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