Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) Peptide
Quick Overview for Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) Peptide (ABIN8106030)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- MARCKS Peptide - C-terminal region
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Sequence
- KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-MARCKS Antibody (ARP60325_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Background
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Background Information: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Alternative Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
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Molecular Weight
- 31kDa
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Gene ID
- 4082
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NCBI Accession
- NP_002347
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UniProt
- P29966
Target
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