Neuro-Oncological Ventral Antigen 1 (NOVA1) (N-Term) Peptide
Quick Overview for Neuro-Oncological Ventral Antigen 1 (NOVA1) (N-Term) Peptide (ABIN8106322)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- NOVA1 Peptide - N-terminal region
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Sequence
- THTGVPIDLD PPDSRKRPLE APPEAGSTKR TNTGEDGQYF LKVLIPSYAA
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Neuro-Oncological Ventral Antigen 1 (NOVA1) peptide
NOVA1 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- NOVA1 Antibody (ARP90851_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))
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Background
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Background Information: Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY. Most likely acts to activate the inclusion of exon E3A in the glycine receptor alpha-2 chain and of exon E9 in gamma-aminobutyric-acid receptor gamma-2 subunit via a distal downstream UCAU-rich intronic splicing enhancer.
Alternative Symbols: Nova-1, G630039L02, 9430099M15Rik
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Molecular Weight
- 52 kDa
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Gene ID
- 664883
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NCBI Accession
- NP_067336
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UniProt
- Q9JKN6
Target
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