Osteocalcin (BGLAP) (N-Term) Peptide
Quick Overview for Osteocalcin (BGLAP) (N-Term) Peptide (ABIN8107422)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- BGLAP Peptide - N-terminal region
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Sequence
- IAGQAGAKPS GAESSKGAAF VSKQEGSEVV KRPRRYLYQW LGAPVPYPDP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-OSTCN Antibody (ARP75949_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Osteocalcin (BGLAP)
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Background
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Background Information: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Alternative Symbols: OC, BGP, OCN
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Molecular Weight
- 11kDa
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Gene ID
- 632
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NCBI Accession
- NP_954642
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UniProt
- P02818
Target
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