Osteoclast Associated Receptor (OSCAR) (C-Term) Peptide
Quick Overview for Osteoclast Associated Receptor (OSCAR) (C-Term) Peptide (ABIN8107423)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- OSCAR Peptide - C-terminal region
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Sequence
- LSQRSEVLVI SWEDSGSSDY TRGNLVRLGL AGLVLISLGA LVTFDWRSQN
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-OSCAR Antibody (ARP63083_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- OSCAR (Osteoclast Associated Receptor (OSCAR))
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Background
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Background Information: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: MGC33613, PIGR3
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Molecular Weight
- 27kDa
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Gene ID
- 126014
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NCBI Accession
- NP_573398
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UniProt
- Q8IYS5
Target
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