Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide
Quick Overview for Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide (ABIN8107603)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- Ptf1a Peptide - N-terminal region
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Sequence
- FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Ptf1a Antibody (ARP37243_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
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Background
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Targeted Subunit: alpha
Background Information: Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Alternative Symbols: PTF1-p48, PTF1p48, bHLHa29
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Molecular Weight
- 35kDa
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Gene ID
- 19213
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NCBI Accession
- NP_061279
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UniProt
- Q9QX98
Target
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