PDZ and LIM Domain 2 (PDLIM2) (N-Term) Peptide
Quick Overview for PDZ and LIM Domain 2 (PDLIM2) (N-Term) Peptide (ABIN8107729)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- PDLIM2 Peptide - N-terminal region
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Sequence
- LHAEAQSKIR QSPSPLRLQL DRSQATSPGQ TNGDSSLEVL ATRFQGSVRT
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-PDLI2 Antibody (ARP75739_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))
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Background
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Background Information: This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Symbols: SLIM, MYSTIQUE
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Molecular Weight
- 38kDa
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Gene ID
- 64236
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UniProt
- Q96JY6
Target
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