Periaxin (PRX) (C-Term) Peptide
Quick Overview for Periaxin (PRX) (C-Term) Peptide (ABIN8107832)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Purpose
- PRX Peptide - C-terminal region
-
Sequence
- SRGQEGDAAP KSPVREKSPK FRFPRVSLSP KARSGSGDQE EGGLRVRLPS
-
-
Periaxin (PRX) peptide
PRX Host: Synthetic BP, IHC, WB
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-PRAX Antibody (ARP75716_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- Periaxin (PRX)
-
Background
-
Background Information: This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
Alternative Symbols: CMT4F
-
Molecular Weight
- 145kDa
-
Gene ID
- 57716
-
UniProt
- Q9BXM0
Target
-
