Phosphodiesterase 1A (PDE1A) (C-Term) Peptide
Quick Overview for Phosphodiesterase 1A (PDE1A) (C-Term) Peptide (ABIN8108065)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- PDE1A Peptide - C-terminal region
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Sequence
- ALRRSNTKGS MSDGSYSPDY SLAAVDLKSF KNNLVDIIQQ NKERWKELAA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- PDE1A Antibody (ARP97619_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PDE1A (Phosphodiesterase 1A (PDE1A))
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Background
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Background Information: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+).
Alternative Symbols: HCAM1, HCAM-1, HSPDE1A, CAM-PDE-1A
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Molecular Weight
- 60 kDa
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Gene ID
- 5136
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NCBI Accession
- NP_001003683
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UniProt
- P54750
Target
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