Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) Peptide
Quick Overview for Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) Peptide (ABIN8108134)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- PIK3R1 Peptide - C-terminal region
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Sequence
- QKGVRQKKLN EWLGNENTED QYSLVEDDED LPHHDEKTWN VGSSNRNKAE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- PIK3R1 Antibody (ARP86869_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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Background
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Background Information: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
Alternative Symbols: p85, AGM7, GRB1, IMD36, p85-ALPHA
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Molecular Weight
- 39 kDa
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Gene ID
- 5295
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NCBI Accession
- NP_001229395
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UniProt
- P27986
Target
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